TRR259 - Aortic Disease
University of Bonn
TRR259 - Aortic Disease
University of Cologne
TRR259 - Aortic Disease
University of Düsseldorf
TRR259 - Aortic Disease
TRR259 - Aortic Disease
TRR259 - Aortic Disease

TRR259 - Aortic Disease 

The TRR259 is a Collaborative Research Center funded by the German Research Foundation (DFG) at the University Bonn, Cologne, and Düsseldorf. In a joint and multidisciplinary effort, we are investigating the molecular and cellular mechanisms of aortic disease holistically, with a particular focus on aortic valve stenosis, aortic aneurysm, and aortic dissection. Prospectively, we envision identifying novel pharmacological, interventional, and surgical targets for diagnostic, preventive, and therapeutic strategies within the frame of translational and clinical studies. 

© UniBonn_UniCologne_UniDuesseldorf

About us

Here you will find information about the TRR259


This page gives you an overview of the TRR259 projects


Here you can find information about the integrated research school

News & Events

Learn more about seminars and events of the TRR259

Gender & Diversity

Find out more about TRR259's efforts on equality and diversity


Here you will find a list of publications


For the 2nd funding period of TRR259 we are looking for PhD students, postdocs and other employees

Jul 2019






Monthly Seminar Series
Prof. Dr. Monika Gladka
04:00 PM - 05:00 PM
Speaker: Prof. Dr. Monika Gladka from the from the Department of Medical Biology (Amsterdam University Medical Centers, Amsterdam) Title:
Prof. Dr. Tomohisa Sakaue: Translational Cardiovascular Surgery
University Hospital ...
04:00 PM - 05:00 PM
Speaker: Prof. Dr. Tomohisa Sakaue from the Department of Cardiovascular and Thoracic Surgery (Ehime Universiy Graduate School of Medicine, Japan) Title: ...
Prof. Dr. T. Kawashima on iBTA in Cardiovascular Surgery
University Hospital ...
04:00 AM - 05:00 AM
Speaker: Prof. Dr. Takkayuki Kawashima from the Department of Cardiovascular Surgery (Oita University Hospital, Japan) Title: Potential of new regenerative ...
Dissecting the role of APRIL in cardiovascular diseases
Düsseldorf, University ...
02:00 AM - 03:00 AM
Speaker: Prof. Dr. Dimitrios Tsiantoulas (Dept. of Laboratory Medicine & Center for Molecular Medicine of the Austrian Academy of Sciences Medical University ...
News & Events

On June 18th, 2024, the University Hospital Düsseldorf successfully hosted the TRR259 International Symposium on Aortic Disease. The event took place in the lecture hall of the Surgery Department, drawing a distinguished group of experts from around the world to discuss cutting-edge research and advancements in the field of aortic disease.

Call for Manuscripts

The journal Bioengineering invites researchers, scientists and experts to contribute their innovative work to the upcoming special issue on Gene Delivery Tools for Biomedical Engineering Applications.

Revolution in Cardiac Surgery: The Aorta is now Recognized as an Independent Organ

For years, our research team in the TRR259 has gathered groundbreaking insights into the aorta. Now, the European Association for Cardio-Thoracic Surgery (EACTS) and the American Society of Thoracic Surgeons (STS) have stipulated that the aorta should be considered as an independent organ in the human body.

Open position: Medical-technical assistant (m/f/d)

The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,306 beds. Our more than 8,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In 2021, the UKB has the fourth-highest case mix index and the best economic result of the university hospitals in Germany and is ranked number 1 of the university hospitals in NRW in the science ranking (LOMV).


Avatar Nehl

Dr. Denise Nehl

Scientific coordinator

Biomedical Center I, Building 13, Floor 3, Room 22

Clinic for Internal Medicine II

Department of Molecular Cardiology

University Hospital Bonn

Venusberg-Campus 1

53127 Bonn

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