TRR259 - Aortic Disease
University of Bonn
TRR259 - Aortic Disease
University of Cologne
TRR259 - Aortic Disease
University of Düsseldorf
TRR259 - Aortic Disease
TRR259 - Aortic Disease
TRR259 - Aortic Disease

TRR259 - Aortic Disease 

The TRR259 is a Collaborative Research Center funded by the German Research Foundation (DFG) at the University Bonn, Cologne, and Düsseldorf. In a joint and multidisciplinary effort, we are investigating the molecular and cellular mechanisms of aortic disease holistically, with a particular focus on aortic valve stenosis, aortic aneurysm, and aortic dissection. Prospectively, we envision identifying novel pharmacological, interventional, and surgical targets for diagnostic, preventive, and therapeutic strategies within the frame of translational and clinical studies. 

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About us

Here you will find information about the TRR259


This page gives you an overview of the TRR259 projects


Here you can find information about the integrated research school

News & Events

Learn more about seminars and events of the TRR259

Gender & Diversity

Find out more about TRR259's efforts on equality and diversity


Here you will find a list of publications

3rd International Symposium 

The 3rd international symposium of the TRR259 will take place from March 23-25, 2022

Jul 2019






Monthly Seminar Series
Precision biomaterials - application to studying valve fibrosis
04:00 PM - 05:00 PM
Speaker: Prof. Kristi S. Anseth (Department of Chemical and Biological Engineering and the BioFrontiers Institute, University of Colorado at Boulder) Title: ...
Emerging role of RNA modifications in vascular health and disease
University Hospital ...
04:00 PM - 05:00 PM
Speaker: Prof. Konstantinos Stellos, Department of Cardiovascular Research, European Center for Angioscience, Heidelberg University. Title: Emerging role ...
Large Artery Stiffness in Health and Disease
04:00 PM - 05:00 PM
Speaker: Prof. Julio Chirinos (Department of Medicine, Perelman School of Medicine, University of Pennsylvania) Title: Large Artery Stiffness in Health ...
Biomechanics and signalling during cardiac valve morphogenesis
Bonn, Teaching building ...
04:00 PM - 05:00 PM
Speaker: Prof. Julien Vermot (Faculty of Engineering, Department of Bioengineering, Imperial College London) Title: Biomechanics and signalling during ...
News & Events
Marfan Research Prize

The Marfan Research Prize 2020/2021 goes to the Experimental Cardiology working group of Clinic III for Internal Medicine at the University Hospital of Cologne and the Medical Faculty.

Diversity Days

On May 31, 2022, the nationwide Diversity Day, initiated by the Diversity Charter, will take place for the 10th time. The University of Bonn is organizing the Diversity Days from May 30 to June 1 to mark this occasion. The three days are organized by the Equal Opportunity and Diversity Unit and the Vice Rectorate for Equal Opportunity and Diversity in cooperation with the Office of Family Services.

Open position: Scientific coordinator (m/f/d) of the integrated graduate school of the TRR259

 The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,306 beds. Our more than 8,000 employees take on tasks in research, teaching, patient care, and public health at the highest level. In 2021, the UKB has the fourth-highest case mix index and the best economic result of the university hospitals in Germany and is ranked number 1 of the university hospitals in NRW in the science ranking (LOMV).

Joint meeting of 14 German SFB research consortia & graduate schools focusing on kidney, heart, and vessels:

On May 5-6, 2022, the TRR259 participated in the first “Joint meeting of German SFB research consortia & graduate schools”, organized by the SFB/TRR219. The meeting took place with 14 associations that focused on kidney, heart, and vessels.


Avatar Enders

Dr. Marika Enders

Scientific coordinator

Biomedical Center I Building 13, 3G, room 022

Venusberg-Campus 1

53127 Bonn

Clinic for Internal Medicine II

+49 228 287-51735

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