TRR259 - Aortic Disease
University of Bonn
TRR259 - Aortic Disease
University of Cologne
TRR259 - Aortic Disease
University of Düsseldorf
TRR259 - Aortic Disease
TRR259 - Aortic Disease
TRR259 - Aortic Disease

TRR259 - Aortic Disease 

The TRR259 is a Collaborative Research Center funded by the German Research Foundation (DFG) at the University Bonn, Cologne, and Düsseldorf. In a joint and multidisciplinary effort, we are investigating the molecular and cellular mechanisms of aortic disease holistically, with a particular focus on aortic valve stenosis, aortic aneurysm, and aortic dissection. Prospectively, we envision identifying novel pharmacological, interventional, and surgical targets for diagnostic, preventive, and therapeutic strategies within the frame of translational and clinical studies. 

© UniBonn_UniCologne_UniDuesseldorf

About us

Here you will find information about the TRR259


This page gives you an overview of the TRR259 projects


Here you can find information about the integrated research school

News & Events

Learn more about seminars and events of the TRR259

Gender & Diversity

Find out more about TRR259's efforts on equality and diversity


Here you will find a list of publications


For the 2nd funding period of TRR259 we are looking for PhD students, postdocs and other employees

Jul 2019






Monthly Seminar Series
Metabolic sensing and endothelial cell transitions
Teaching building, ...
04:00 PM - 05:00 PM
Speaker: Prof. Dr. Sofia-Iris Bibli (Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main) Title: ...
Aortic heterogeneity as the basis for development of aortopathies
University Hospital ...
04:00 PM - 05:00 PM
Speaker: Alan Daugherty (University of Kentucky, USA, Director Cardiovascular Research Center). Title: Aortic heterogeneity as the basis for development of ...
Clonal hematopoiesis + acceleration of aortic valve disease
Teaching building, ...
04:00 PM - 05:00 PM
Speaker: Prof. Dr. Wesley Abplanalp (Institute of Cardiovascular Regeneration, Goethe University Frankfurt, Frankfurt am Main); Topic: The role of clonal ...
Novel targets to prevent and treat coronary artery disease
03:00 PM - 04:00 PM
Speaker: PD Dr. Thorsten Kessler (German Heart Centre Munich, Department of Cardiology, Technical University of Munich); Topic: Identification and ...
News & Events
Open position: Medical-technical assistant (m/f/d)

The University Hospital Bonn (UKB) is a maximum care hospital with more than 1,306 beds. Our more than 8,000 employees take on tasks in research, teaching and patient care as well as in public health at the highest level. In 2021, the UKB has the fourth-highest case mix index and the best economic result of the university hospitals in Germany and is ranked number 1 of the university hospitals in NRW in the science ranking (LOMV).

TRR259 kickoff event of the 2nd funding period

On the sunny day of August 14, 2023, all scientists from the Düsseldorf site gathered for a kick-off event of the 2nd funding period of our TRR259 at Scotti’s Restaurant.

Lindau Nobel Laureate Meeting

This year brings a very special honor as Dr. Andreas Zietzer has been selected to attend the 72nd Lindau Nobel Laureate Meeting. The participants had to undergo a lengthy application process to be eligible for the conference. A total of 635 young scientists from around the world have been invited to the meeting. As part of #LINO23, the selected participants can look forward to engaging talks, Agora discussions, and panel sessions, but most importantly, personal interactions with Nobel laureates and other young scientists.

TRR259 research on extracellular vesicles presented at the international conference ISEV

The International Society for Extracellular Vesicles (ISEV) 2023 conference was held in Seattle, Washington, attracting researchers, scientists, and professionals from various disciplines and backgrounds. The event spanned over 17-21 May, providing a comprehensive platform for attendees to exchange knowledge, collaborate, and explore the latest developments in extracellular vesicles (EV) research.


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