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TRR259_Logo_Rund_TransparentVaccination in Atherosclerosis 

Felix Sebastian Nettersheim, Lauren De Vore and Holger Winkels

Cells 2020,Nov 30, 9, 2560, https://doi.org/10.3390/cells9122560


TRR259_Logo_Rund_TransparentThe role of noncoding RNAs during aortic valve stenosis

Goody, Philip Roger, Mohammed Rabiul Hosen, Dominik Christmann, Sven Thomas Niepmann, Andreas Zietzer, Matti Adam, Florian Bönner, Sebastian Zimmer, Georg Nickenig, and Felix Jansen

European Heart Journal 41(Supplement_2), 2020, Nov 25, doi: 10.1093/ehjci/ehaa946.1870


TRR259_Logo_Rund_TransparentMicroRNA-mediated vascular intercellular communication is altered in chronic kidney disease

Andreas Zietzer; Eva Steffen; Sven Niepmann; Philip Düsing; Mohammed Rabiul Hosen; Weiyi Liu; Paul Jamme; Baravan Al-Kassou; Philipp Roger Goody; Sebastian Zimmer; Katrin S Reiners; Alexander Pfeifer; Michael Böhm; Nikos Werner; Georg Nickenig; Felix Jansen,

Cardiovascular Research cvaa322, 2020 Nov. 02, https://doi.org/10.1093/cvr/cvaa322


TRR259_Logo_Rund_TransparentReelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases

Krueger, Irena, Lothar Gremer, Lena Mangels, Meike Klier, Kerstin Jurk, Dieter Willbold, Hans H. Bock, and Margitta Elvers 

Arteriosclerosis, Thrombosis, and Vascular Biology, 2020 Oct, 40(10):2391–2403. doi: 10.1161/ATVBAHA.120.314902


TRR259_Logo_Rund_TransparentIntegrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits

Marina A. Heuschkel, Nikolaos T. Skenteris, Joshua D. Hutcheson, Dewy D. van der Valk, Juliane Bremer, Philip Goody, Jesper Hjortnaes, Felix Jansen, Carlijn V.C. Bouten, Antoon van den Bogaerdt, Ljubica Matic,
Nikolaus Marx and Claudia Goettsch

Cells 2020 Sep 24, 9(10), 2164; https://doi.org/10.3390/cells9102164
 


TRR259_Logo_Rund_TransparentPulmonary hypertension associated with left-sided heart failure

Adler J, Gerhardt F, Wissmüller M, Adler C, Baldus S, Rosenkranz S. Pulmonary hypertension associated with left-sided heart failure. Curr Opin Cardiol. 2020 Sep 21. doi: 10.1097/HCO.0000000000000791. Epub ahead of print. PMID: 32969856


TRR259_Logo_Rund_Transparent  Hyperlipidemia does not affect development of elastase-induced abdominal aortic aneurysm in mice

Joscha Mulorz, Joshua Michael Spin, Hans Christian Beck, My Linh Tha Thi, Markus Udo Wagenhäuser, Lars Melholt Rasmussen, Jes Sanddal Lindholt, Philip Shih Chung Tsao, Lasse Bach Steffensen

Atherosclerosis, 2020 Aug 29, Volume 311, 73 – 83, https://doi.org/10.1016/j.atherosclerosis.2020.08.012


TRR259_Logo_Rund_TransparentNitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis

Mollenhauer M, Mehrkens D, Klinke A, Lange M, Remane L, Friedrichs K, Braumann S, Geißen S, Simsekyilmaz S, Nettersheim FS, Lee S, Peinkofer G, Geisler AC, Geis B, Schwoerer AP, Carrier L, Freeman BA, Dewenter M, Luo X, El-Armouche A, Wagner M, Adam M, Baldus S, Rudolph V. Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis. Sci Rep. 2020 Sep 18;10(1):15319. doi: 10.1038/s41598-020-71870-6. PMID: 32948795.


TRR259_Logo_Rund_TransparentRisk modeling in transcatheter aortic valve replacement remains unsolved: an external validation study in 2946 German patients.

Wolff G, Shamekhi J, Al-Kassou B, Tabata N, Parco C, Klein K, Maier O, Sedaghat A, Polzin A, Sugiura A, Jung C, Grube E, Westenfeld R, Icks A, Zeus T, Sinning JM, Baldus S, Nickenig G, Kelm M, Veulemans V. 

Clin Res Cardiol. 2020 Aug 26. doi: 10.1007/s00392-020-01731-9. Epub ahead of print. PMID: 32851491.


TRR259_Logo_Rund_TransparentMeta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas

Zernecke, Alma, Holger Winkels, Clément Cochain, Jesse W. Williams, Dennis Wolf, Oliver Soehnlein, Clint S. Robbins, Claudia Monaco, Inhye Park, Coleen A. McNamara, Christoph J. Binder, Myron I. Cybulsky, Corey A. Scipione, Catherine C. Hedrick, Elena V. Galkina, Tin Kyaw, Yanal Ghosheh, Huy Q. Dinh, and Klaus Ley

Circulation Research, 2020 Jul 16, 127(3):402–26. doi: 10.1161/CIRCRESAHA.120.316903


The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles

Andreas Zietzer, Mohammed Rabiul Hosen, Han Wang, Philip Roger Goody, Marc Sylvester, Eicke Latz, Georg Nickenig, Nikos Werner & Felix Jansen

 

Journal of Extracellular Vesicles 2020 Jul 02, 9:1, 1786967, DOI: 10.1080/20013078.2020.1786967


Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

Thorsten Gnad, Gemma Navarro, Minna Lahesmaa, Laia Reverte-Salisa, Francesca Copperi, Arnau Cordomi, Jennifer Naumann, Aileen Hochhäuser, Saskia Haufs-Brusberg, Daniela Wenzel, Frank Suhr, Naja Zenius Jespersen, Camilla Scheele, Volodymyr Tsvilovskyy, Christian Brinkmann, Joern Rittweger, Christian Dani, Mathias Kranz, Winnie Deuther-Conrad, Holger K. Eltzschig, Tarja Niemi, Markku Taittonen, Peter Brust, Pirjo Nuutila, Leonardo Pardo, Bernd K. Fleischmann, Matthias Blüher, Rafael Franco, Wilhelm Bloch, Kirsi A. Virtanen, Alexander Pfeifer

Cell Metabolism, 2020 Junehttps://doi.org/10.1016/j.cmet.2020.06.006

TRR259_Logo_Rund_TransparentSustained Immunoparalysis in Endotoxin-Tolerized Monocytic Cells

Christina K. Weisheit, Alexandra Klüners, Lennart Wild, Alexandra Casalter, Stefanie Heilmann-Heimbach, Sugirthan Sivalingam, Jan L. Kleiner, Stefan F. Ehrentraut, Andreas Hoeft, Stilla Frede, and Heidi Ehrentraut

Mediators of Inflammation, 2020 Jun 13, https://doi.org/10.1155/2020/8294342


 

TRR259_Logo_Rund_TransparentMicroRNAs As Master Regulators of Atherosclerosis: From Pathogenesis to Novel Therapeutic Options

Mohammed Rabiul Hosen, Philip Roger Goody, Andreas Zietzer, Georg Nickenig, and Felix Jansen

Antioxidants & Redox Signaling 2020 Junehttps://doi.org/10.1089/ars.2020.8107


TRR259_Logo_Rund_TransparentHot spot 19F magnetic resonance imaging of inflammation

Pascal Bouvain, Sebastian Temme, Ulrich Flögel

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2020 [published online ahead of print, 2020 May 7].e1639.doi:10.1002/wnan.1639


TRR259_Logo_Rund_Transparent Basic Biology of Extracellular Matrix in the Cardiovascular System, Part 1/4: JACC Focus Seminar

del Monte-Nieto, Gonzalo, Jens W. Fischer, Daniel J. Gorski, Richard P. Harvey, and Jason C. Kovacic

 

Journal of the American College of Cardiology, 2020 May 5, 75(17):2169–88.

 

doi: https://doi.org/10.1016/j.jacc.2020.03.024.


Thymic stromal lymphopoietin is a key cytokine for the immunomodulation of atherogenesis with Freund's adjuvant

Martin Steinmetz, Ludivine Laurans, Sarah Nordsiek, Lena Weiß, Bieke van der Veken, Padmapriya Ponnuswamy, Bruno Esposito, Marie Vandestienne, Andreas Giraud, Cristina Göbbel, Eva Steffen, Tobias Radecke, Stephane Potteaux, Georg Nickenig, Tienush Rassaf, Alain Tedgui, Ziad Mallat

Journal of Cellular and Molecular Medicine 2020 May;24(10) 5731-5739; DOI: 10.1111/jcmm.15235

PMID: 32285594

 


TRR259_Logo_Rund_TransparentNew Insights into the Regulation of Apoptosis, Necroptosis, and Pyroptosis by Receptor Interacting Protein Kinase 1 and Caspase-8

Robin Schwarzer, Lucie Laurien, and Manolis Pasparakis

Current Opinion in Cell Biology, 2020 April, 63:186–93. https://doi.org/10.1016/j.ceb.2020.02.004


In vivo detection of programmed cell death during mouse heart development

Kristel Martínez-Lagunas, Yoshifumi Yamaguchi, Cora Becker, Caroline Geisen, Marco C. DeRuiter, Masayuki Miura, Bernd K. Fleischmann and Michael Hesse

Cell Death & Differentiation 2020 Apr; 27(4):1398-1414, DOI: 10.1038/s41418-019-0426-2

PMID: 31570857



TRR259_Logo_Rund_TransparentAortic Valve Stenosis – From Basic Mechanisms to Novel Therapeutic Targets

Philip Roger Goody, Mohammed Rabiul Hosen, Dominik Christmann, Sven Thomas Niepmann, Andreas Zietzer, Matti Adam, Florian Bönner, Sebastian Zimmer, Georg Nickenig, Felix Jansen

Arteriosclerosis, Thrombosis, and Vascular Biology 2020 Apr;40(4):885–900; DOI: 10.1161/ATVBAHA.119.313067

PMID: 32160774


High-Sensitivity Troponin T Testing: Consequences on Daily Clinical Practice and Effects on Diagnosis of Myocardial Infarction

Christian Frédéric Zachoval, Ramona Dolscheid-Pommerich, Ingo Graeff, Bernd Goldschmidt, Andreas Grigull, Birgit Stoffel-Wagner, Georg Nickenig, Sebastian Zimmer 

J Clin Med. 2020 Mar 12;9(3):775. doi: 10.3390/jcm9030775.

PMCID: PMC7141275


TRR259_Logo_Rund_TransparentBMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics

Christian Hiepen, Jerome Jatzlau, Susanne Hildebrandt, Branka Kampfrath, Melis Goktas, Arunima Murgai, Jose Luis Cuellar Camacho, Rainer Haag, Clemens Ruppert, Gerhard Sengle, Elisabetta Ada Cavalcanti-Adam, Kerstin G. Blank, Petra Knaus

PLOS Biology 17(12): e3000557. https://doi.org/10.1371/journal.pbio.3000557


Intravascular Lithotripsy in Calcified Coronary Lesions: A Prospective, Observational, Multicenter Registry

Adem Aksoy, Carlos Salazar, Marc Ulrich Becher, Vedat Tiyerili, Marcel Weber, Felix Jansen, Alexander Sedaghat, Sebastian Zimme, Jürgen Leick, Eberhard Grube, Nieves Gonzalo, Jan-Malte Sinning, Javier Escaned, Georg Nickenig, Nikos Werner

 

Circ Cardiovasc Interv. 2019 Nov;12(11):e008154. DOI: 10.1161/CIRCINTERVENTIONS.119.008154.

 

PMID: 31707803


TRR259_Logo_Rund_TransparentHDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

 

Malhotra, R., Mauer, A.C., Lino Cardenas, C.L. et al. 

 

Nat Genet, 2019 Oct 28, 51, 1580–1587 (2019). https://doi.org/10.1038/s41588-019-0514-8


TRR259_Logo_Rund_TransparentOf Vesicles and Viruses - Why Statins Are Good for HIV Patients

Philip Roger Goody, Felix Jansen, Georg Nickenig

Circulation Research, 2019 Oct 10; 125:821-823. https://doi.org/10.1161/CIRCRESAHA.119.315908


Graded Murine Wire-Induced Aortic Valve Stenosis Model Mimics Human Functional and Morphological Disease Phenotype

 

Sven Thomas Niepmann, Eva Steffen, Andreas Zietzer, Matti Adam, Julia Nordsiek, Isabella Gyamfi-Poku, Kerstin Piayda, Jan-Malte Sinning, Stephan Baldus, Malte Kelm, Georg Nickenig, Sebastian Zimmer, Christine Quast

 

Clin Res Cardiol. 2019 Aug;108(8):847-856. DOI: 10.1007/s00392-019-01413-1.

 

PMID: 30767058

 


cGMP manipulation in cardiometabolic disease: chances and challenges.

Jens Jordan, Staffan Hildebrand, Alexander Pfeifer


Curr Opin Cardiol. 2019 Juli;34(4):376-383. DOI:10.1097/HCO.0000000000000630

 

PMID: 30994530


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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