TRR259 - Aortic Disease
University of Bonn
TRR259 - Aortic Disease
University of Cologne
TRR259 - Aortic Disease
University of Düsseldorf
TRR259 - Aortic Disease
TRR259 - Aortic Disease
TRR259 - Aortic Disease

Publications of the TRR259 - 2023

2023


Human and porcine aortic valve endothelial and interstitial cell isolation and characterization

Nehl D, Goody, PR, Maus K, Pfeifer A, Aikawa E, Bakhtiary F, Zimmer S, Nickenig G, Jansen F, Hosen MR.

Front Cardiovasc Med. 2023 Jun 20; doi.org/10.3389/fcvm.2023.1151028

Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state

Bosmans LA, van Tiel CM, Aarts SABM, Willemsen L, Baardman J, van Os BW, Toom MD, Beckers L, Ahern DJ, Levels JHM, Jongejan A, Moerland PD, Verberk SGS, den Bossche JV, de Winther MMPJ, Weber C, Atzler D, Monaco C, Gerdes N, Shami A, Lutgens E. 

Cardiovasc Res. 2023 May 22;119(5):1146-1160. doi: 10.1093/cvr/cvac084.

Chronic anemia is associated with systemic endothelial dysfunction

Chennupati R, Solga I, Wischmann P, Dahlmann P, Celik FG, Pacht D, Şahin A, Yogathasan V, Hosen MR, Gerdes N, Kelm M, Jung C. 

Front Cardiovasc Med. 2023 May 10;10:1099069. doi: 10.3389/fcvm.2023.1099069.

Chronic anemia is associated with systemic endothelial dysfunction

Wischmann P, Dahlmann P, Celik FG, Pacht D, Şahin A, Yogathasan V, Hosen MR, Gerdes N, Kelm M, Jung C.

Frontiers in Cardiovascular Medicine 2023;10.

Targeting microRNA-10 in glioma; a focus with potential therapeutic application in genome editing

Maus K, Jansen F, Hosen MR. 

Molecular Therapy - Nucleic Acids 2023;32:504–506. doi:10.1016/j.omtn.2023.04.008.

Targeting microRNA-10 in glioma; a focus with potential therapeutic application in genome editing

Maus K, Jansen F, Hosen MR. 

Molecular Therapy - Nucleic Acids 2023;32:504–506. doi:10.1016/j.omtn.2023.04.008.

Impact of transradial versus transfemoral access for preprocedural coronary angiography on TAVR-associated complications

Al-Kassou B, Al-Shaikh H, Aksoy A, Shamekhi J, Zietzer A, Sugiura A, Veulemans V, Adam M, Grube E, Bakhtiary F, Zimmer S, Kelm M, Baldus S, Nickenig G, Sedaghat A

IJC Heart & Vasculature 2023;46:101205. doi:10.1016/j.ijcha.2023.101205.

Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory latent TGFβ-binding site

Godwin ARF, Dajani R, Zhang X, Thomson J, Holmes DF, Adamo CS, Sengle G, Sherratt MJ, Roseman AM, Baldock C. 

Nat Struct Mol Biol. 2023 Apr 20. doi: 10.1038/s41594-023-00950-8.

Inhibition of CD40-TRAF6 signaling protects against aneurysm development and progression

Ommer-Bläsius M, Vajen T, Elster C, Verheyen S, Pfeiler S, Quast C, Odendahl J, Lang A, Kelm M, Lutgens E, Gerdes N. 

BioRxiv 2023:2023.03.24.534110. doi:10.1101/2023.03.24.534110

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG

Cardiovasc Res. 2023 Mar 17;119(1):45-63. doi: 10.1093/cvr/cvac031.

Colchicine Protects against Ethanol-Induced Senescence and Senescence-Associated Secretory Phenotype in Endothelial Cells

Zhou H, Khan D, Gerdes N, Hagenbeck C, Rana M, Cornelius JF, Muhammad S

Antioxidants. 2023; 12(4):960. https://doi.org/10.3390/antiox12040960

Platelet pannexin-1 channels modulate neutrophil activation and migration but not the progression of abdominal aortic aneurysm.

Metz LM, Feige T, de Biasi L, Ehrenberg A, Mulorz J, Toska LM, Reusswig F, Quast C, Gerdes N, Kelm M, Schelzig H, Elvers M.

Front Mol Biosci. 2023 Mar 6;10:1111108. doi: 10.3389/fmolb.2023.1111108.

Increased IKKϵ protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency

Wegner J, Hunkler C, Ciupka K, Hartmann G, Schlee M

Front Immunol. 2023 Mar 3;14:1073608. doi: 10.3389/fimmu.2023.1073608.

BMPER Improves Vascular Remodeling and the Contractile Vascular SMC Phenotype

Pankratz F, Maksudova A, Goesele R, Meier L, Proelss K, Marenne K, Thut AK, Sengle G, Correns A, Begelspacher J, Alkis D, Siegel PM, Smolka C, Grundmann S, Moser M, Zhou Q, Esser JS. 

Int J Mol Sci. 2023 Mar 3;24(5):4950. doi: 10.3390/ijms24054950.

BMPER Improves Vascular Remodeling and the Contractile Vascular SMC Phenotype

Pankratz F, Maksudova A, Goesele R, Meier L, Proelss K, Marenne K, Thut A-K, Sengle G, Correns A, Begelspacher J, Alkis D, Siegel PM, Smolka C, Grundmann S, Moser M, Zhou Q, Esser JS

International Journal of Molecular Sciences. 2023; 24(5):4950. https://doi.org/10.3390/ijms24054950

GPCR in Adipose Tissue Function-Focus on Lipolysis

Malfacini D, Pfeifer A.

Biomedicines. 2023 Feb 16;11(2):588. doi: 10.3390/biomedicines11020588.

Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets

Han C, Ren P, Mamtimin M, Kruk L, Sarukhanyan E, Li C, Anders HJ, Dandekar T, Krueger I, Elvers M, Goebel S, Adler K, Münch G, Gudermann T, Braun A, Mammadova-Bach E

Biomedicines. 2023 Feb 1;11(2):423. doi: 10.3390/biomedicines11020423.

Non-invasive mapping of systemic neutrophil dynamics upon cardiovascular injury

Bouvain P, Ding Z, Kadir S, Kleimann P, Kluge N, Tiren Z-B, Steckel B, Flocke V, Zalfen R, Petzsch P, Wachtmeister T, John G, Subramaniam N, Krämer W, Strasdeit T, Mehrabipour M, Moll JM, Schubert R, Ahmadian MR, Bönner F, Boeken U, Westenfeld R, Engel DR, Kelm M, Schrader J, Köhrer K, Grandoch M, Temme S, Flögel U  

Nat Cardiovasc Res 2023:1–18. doi:10.1038/s44161-022-00210-w.

Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets

Han, C.; Ren, P.; Mamtimin, M.; Kruk, L.; Sarukhanyan, E.; Li, C.; Anders, H.-J.; Dandekar, T.; Krueger, I.; Elvers, M.; Goebel, S.; Adler, K.; Münch, G.; Gudermann, T.; Braun, A.; Mammadova-Bach, E.

Biomedicines 2023, 11, 423. https://doi.org/10.3390/biomedicines11020423

Aktives Targeting zur Visualisierung von thrombotischen Prozessen mittels 19F-MRT

Temme, S., Kleimann, P., Grandoch, M. et al.

Gefässchirurgie 28, 52–57 (2023). https://doi.org/10.1007/s00772-022-00961-7

Toll-like receptor-3 contributes to the development of aortic valve stenosis

Niepmann ST, Willemsen N, Boucher AS, Stei M, Goody P, Zietzer A, Bulic M, Billig H, Odainic A, Weisheit CK, Quast C, Adam M, Schmidt SV, Bakhtiary F, Jansen F, Nickenig G, Latz E, Zimmer S

Basic Res Cardiol. 2023 Feb 1;118(1):6. doi: 10.1007/s00395-023-00980-9

Optimal protamine-to-heparin dosing ratio for the prevention of bleeding complications in patients undergoing TAVR-A multicenter experience

Al-Kassou B, Veulemans V, Shamekhi J, Maier O, Piayda K, Zeus T, Aksoy A, Zietzer A, Meertens M, Mauri V, Weber M, Sinning JM, Grube E, Adam M, Bakhtiary F, Zimmer S, Baldus S, Kelm M, Nickenig G, Sedaghat A.

Clin Cardiol. 2023 Jan;46(1):67-75. doi: 10.1002/clc.23936.

RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma

Lambing S, Tan YP, Vasileiadou P, Holdenrieder S, Müller P, Hagen C, Garbe S, Behrendt R, Schlee M, van den Boorn JG, Bartok E, Renn M, Hartmann G

J Mol Cell Biol. 2023 Jan 10:mjad001. doi: 10.1093/jmcb/mjad001.

Impact of different guidewires on the implantation depth using the largest self-expandable TAVI device

Veulemans V, Wilde N, Wienemann H, Adrichem R, Hokken TW, Al-Kassou B, Shamekhi J, Mauri V, Maier O, Jung C, Horn P, Adam M, Nickenig G, Baldus S, Van Mieghem NM, Kelm M, Sedaghat A, Zeus T

Front Cardiovasc Med. 2023 Jan 5;9:1064916. doi: 10.3389/fcvm.2022.1064916.

Targeting of bone morphogenetic protein complexes to heparin/heparan sulfate glycosaminoglycans in bioactive conformation

Spanou CES, Wohl AP, Doherr S, Correns A, Sonntag N, Lütke S, Mörgelin M, Imhof T, Gebauer JM, Baumann U, Grobe K, Koch M, Sengle G

FASEB J. 2023 Jan;37(1):e22717. doi: 10.1096/fj.202200904R. PMID: 36563024.

Protective Effects of Therapeutic Neutrophil Depletion and Myeloperoxidase Inhibition on Left Ventricular Function and Remodeling in Myocardial Infarction

Guthoff H, Hof A, Klinke A, Maaß M, Konradi J, Mehrkens D, Geißen S, Nettersheim FS, Braumann S, Michaelsson E, Nies RJ, Lee S, Redzinski M-C, Peters VBM, Nemade HN, von Stein P, Winkels H, Rudolph V, Baldus S, Adam M, Mollenhauer M. 

Antioxidants 2023;12:33. doi:10.3390/antiox12010033.

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