TRR259 - Aortic Disease
University of Bonn
TRR259 - Aortic Disease
University of Cologne
TRR259 - Aortic Disease
University of Düsseldorf
TRR259 - Aortic Disease
TRR259 - Aortic Disease
TRR259 - Aortic Disease

Members of the TRR259

Here you will find an overview of the project leaders of the TRR259.

Research Area A

Non-resident mechanisms of aortic and aortic valve disease

The Research area A (systemic, non-resident mechanisms) comprises factors, signals, and cells (such as leukocytes, red blood cells, platelets, and adipocytes) and their respective messengers, that are not originating from or residing in aortic tissue. We have divided this area into an inflammatory and a non-inflammatory section.

Eine Wissenschaftlerin und ein Wissenschaftler arbeiten hinter einer Glasfassade und mischen Chemikalien mit Großgeräten.
© COLOURBOX_cb_29075120

Research Area A


                                                     Project A01

Research Area B

Resident mechanisms of aortic and aortic valve disease

The Research area B (Resident mechanisms) covers processes initiated or caused by pathways within or between resident cells (section 1) and the ECM (section 2).

Eine Wissenschaftlerin und ein Wissenschaftler arbeiten hinter einer Glasfassade und mischen Chemikalien mit Großgeräten.
© COLOURBOX_cb_25812517

Research Area B

Project B10


Research Area C

The ultimate goal of the consortium is to improve prevention, detection and treatment of aortic disease. For this, translation of preclinical findings to patient care is essential and requires primary cells, cell organoids, small and large animal models, as well as human studies in order to holistically perform disease modelling, disease phenotyping, diagnostics, risk stratification and therapeutic interventions. Projects in research area C are dedicated to this translational focus. 

Eine Wissenschaftlerin und ein Wissenschaftler arbeiten hinter einer Glasfassade und mischen Chemikalien mit Großgeräten.
© Cristian Storto Fotografia

Research Area C


Research Area D

Eine Wissenschaftlerin und ein Wissenschaftler arbeiten hinter einer Glasfassade und mischen Chemikalien mit Großgeräten.
© COLOURBOX_cb31787045

Research Area D

MGK


Project Z

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