S01
S01
S01
S01
S01
S01

S01-Animal models

The entire consortium of TRR259 is dependent on complex animal models that adequately resemble the molecular pathologies of aortic valve stenosis (AS) and aortic aneurysm (AA) formation. Project S01 serves as a central unit for a) providing animal models, b) comprehensive imaging and phenotyping, c) training of surgical and imaging skills, and d) quality management and assurance across the research sites in Bonn, Cologne and Düsseldorf. Project S01 developed and deeply phenotyped several animal models of experimental aortic valve stenosis and aortic aneurysm formation and has generated extensive baseline data sets for quality control during the first funding period. Furthermore, it has provided the scientific and personnel infrastructure to develop and establish a large animal model of aortic aneurysm formation in pigs. In the upcoming second funding period, S01 will not only continue its efforts to offer highly reliable experimental animal models but also coordinate the development and characterisation of novel techniques and large-animal models of aortic disease.


Contacts

Avatar Zimmer

Prof. Dr. Sebastian Zimmer

Principal Investigator (Bonn)

Heart Center, Building 26

Venusberg-Campus 1

53127 Bonn

Heart Center, Building 26

+49 228 287-16670

Avatar Sengle

Prof. Dr. Gerhard Sengle

Principal Investigator (Cologne)

Joseph-Stelzmann-Strasse 52

50931 Köln

Center for Biochemistry II

+49 221 478-97260

Avatar Quast

Dr. Christine Quast

Principal Investigator (Düsseldorf)

Moorenstraße 5

40225 Düsseldorf

Division of Cardiology, Pulmonology and Vascular Medicine

+49 (0) 211 81 08143

Avatar Niepmann

Dr. Sven Thomas Niepmann

Postdoctoral Researcher

Department of Molecular Cardiology

Venusberg-Campus 1

53127 Bonn

Clinic for Internal Medicine II

+49 228 287-51485

Avatar Bulic

Dr. Marko Bulic

Postdoctoral Researcher

Biomedical Center I Building 13, 3OG

Venusberg-Campus 1

53127 Bonn

Clinic for Internal Medicine II

+49 228 287-

Avatar Nöthel

Dr. Moritz Nöthel

Postdoctoral Researcher

Biomedical Center I, Building 13, 3OG

Venusberg-Campus 1

53127 Bonn

Clinic for Internal Medicine II

+49 228 287-51486

Avatar Billig

Dr. Hannah Billig

Postdoctoral Researcher

Biomediacl Center I, Building 13, 3OG

Venusberg-Campus 1

53127 Bonn

Clinic for Internal Medicine II

+49 228 287 51485

Avatar Ansgar

Dr. Ackerschott Ansgar

Postdoctoral Researcher

Venusberg-Campus 1

53127 Bonn

Medizinische Klinik II für Kardiologie, Angiologie und Pneumologie; Molekulare Kardiologie

0228-28751486

Avatar Adler

Dr. Sandra Adler

Scientific Coordinator S01

Biomedical Center I Building 13, 3G, room 010

Venusberg-Campus 1

53127 Bonn

Department of Molecular Cardiology

+49 228 287-51484

Avatar Stei

Dr. med. vet. Marta Stei

Veterinarian

Biomedical Center I Building 13, 3OG

Venusberg-Campus 1

53127 Bonn

Department of Molecular Cardiology

+ 49 (0) 228 287-51484

Avatar Sonntag-Bensch

Dr. Dagmar Sonntag-Bensch

Veterinarian

Zentrum für Biochemie

+49 478 81-

Avatar Martinac

Gloria Martinac

Technical Assistant

Biomedical Center I, Building 13, 3OG

Venusberg-Campus 1

53127 Bonn

Department of Molecular Cardiology

+49 228 287-51483

Avatar Fuchs

Pia Fuchs

Technical Assistant

Biomedical Center I, Building 13, 3OG

Venusberg-Campus 1

53127 Bonn

Department of Molecular Cardiology

+49 228 287-51483

Avatar Pauli

Julia Pauli

Technical Assistant

Moorenstraße 5

40225 Düsseldorf

Division of Cardiology, Pulmonology and Vascular Medicine

+49 211-81 15898

Avatar Panatzek

Henning Panatzek

Technical Assistant

+49 228 287-51483

Wird geladen