The study entitled “Circulating microRNA-122-5p correlates with improvement in left-ventricular function after transcatheter aortic valve replacement and regulates viability of cardiomyocytes via extracellular vesicles”.
Dr. Hosen with his group demonstrated that circulating miR-122-5p is upregulated via extracellular vesicles in aortic valve stenosis (AVS)-patients with persistent LV dysfunction after transcatheter aortic valve replacement (TAVR) and can be an important predictor of cardiac dysfunction in patients with low left ventricular ejection fraction (LVEF) after the TAVR procedure.
This study is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – Project-ID 397484323 – TRR 259 (Project B04).