Project B
The Research area B (Resident mechanisms) covers processes initiated, or caused by pathways within or between resident cells (section 1) and the ECM (section 2).
B01 - B07: Role of resident cells
B01 - Jun.-Prof. Daniela Wenzel / Prof. Bernd Fleischmann
Endothelial disease mechanisms involved in calcific aortic valve stenosis and aortic aneurysm formation in mice and humans
B03 - PD Dr. Florian Bönner / Prof. Ulrich Flögel
The role of local and systemic hemodynamic forces in the development of aortic disease
B04 - Prof. Alexander Pfeifer / PD Dr. Felix Jansen
EVs as intercellular messengers in aortic valve calcification
B05 - Prof. Manolis Pasparakis / PD Dr. Matti Adam
Necroptosis in aortic aneurysm disease - significance of inflammation in MLKL dependent cell death
B06 - Prof. Stephan Rosenkranz
Role of PI3-kinase isoform p110α for vascular integrity and aortic aneurysm formation
B07 - Prof. M. Markus Nöthen / Dr. Baravan Al-Kassou /
Prof. Johannes Schumacher
Genes underlying aortic valve disease
B08 - B09: Role of ECM
B08 - Prof. Maria Grandoch / Prof. Jens W. Fischer
Importance of hyaluronan-rich extracellular matrix for inflammation and structural remodeling in abdominal aortic aneurysms
B09 - Prof. Dr. Gerhard Sengle
Dysregulated extracellular signaling pathways in aortic aneurysm formation in Marfan syndrome
